Trypanosomiasis research has deep roots at the STI. Professor Rudolf Geigy, the founder and first director of the institute, took a great interest in sleeping sickness and started studies in Tanzania in the late 1960s on the role of wild animals as reservoirs for human trypanosomiasis. In 1970 and 1971, I worked as a student in Uganda at the East African Trypanosomiasis Research Organization EATRO ; , by that time the leading institution in sleeping sickness research; but this freshly established collaboration met with a sudden end after Idi Amin came into power and took the country into a civil war that lasted for 15 years. Since then, the STI has maintained an active research group working on tsetse flies and trypanosomes. Over the years, many scientists, technicians and students have contributed to the success and recognition of this group. For the last 30 years, the sleeping sickness research of the STI has been focused on field studies in Tanzania and Uganda combined with laboratory research in Basel. This balance between field and lab research has been maintained throughout and still represents one of the strengths of the STI. Based on a growing expertise in methodologies for cultivating the parasites in vitro and using them for screening purposes, my group's interest moved towards chemotherapy. About 7 years ago, the group also embarked on pharmacological research on melarsoprol, which culminated in the proposition of a.
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Troesophageal reflux with whey- and casein-based formulas in infants and in children with severe neurological impairment. J Pediatr Gastroenterol Nutr. 1996; 22: 48-55. Kelly KJ, Lazenby AJ, Rowe PC, Yardley JH, Perman JA, Sampson HA. Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acidbased formula. Gastroenterology. 1995; 109: 1503-1512. Vandenplas Y, Sacre L, Loeb H. Effects of formula feeding on gastric acidity time and oesophageal pH monitoring data. Eur J Pediatr. 1988; 148: 152-154. Sutphen JL, Dillard VL. Medium chain triglyceride in the therapy of gastroesophageal reflux. J Pediatr Gastroenterol Nutr. 1992; 14: 38-40. Sutphen JL, Dillard VL. Effect of feeding volume on early postcibal gastroesophageal reflux in infants. J Pediatr Gastroenterol Nutr. 1988; 7: 185-188. Blumenthal I, Lealman GT. Effect of posture on gastro-oesophageal reflux in the newborn. Arch Dis Child. 1982; 57: 555-556. Vandenplas Y, Sacre-Smits L. Gastro-oesophageal reflux in infants: evaluation of treatment by pH monitoring. Eur J Pediatr. 1987; 146: 504-507. Vandenplas Y, Sacre L. Milk-thickening agents as a treatment for gastroesophageal reflux. Clin Pediatr Phila ; . 1987; 26: 66-68. Tobin JM, McCloud P, Cameron DJ. Posture and gastro-oesophageal reflux: a case for left lateral positioning. Arch Dis Child. 1997; 76: 254-258. Orenstein SR, Whitington PF. Positioning for prevention of infant gastroesophageal reflux. J Pediatr. 1983; 103: 534-537. Sutphen JL, Dillard VL, Pipan ME. Antacid and formula effects on gastric acidity in infants with gastroesophageal reflux. Pediatrics. 1986; 78: 55-57. Gouyon JB, Boggio V, Fantino M, Gillot I, Schatz B, Vallin A. Smectite reduces gastroesophageal reflux in newborn infants. Dev Pharmacol Ther. 1989; 13: 46-50. Orenstein SR. Prone positioning in infant gastroesophageal reflux: is elevation of the head worth the trouble? J Pediatr. 1990; 117 pt 1 ; : 184-187. Orenstein SR, Whitington PF, Orenstein DM. The infant seat as treatment for gastroesophageal reflux. N Engl J Med. 1983; 309: 760-763. Borrelli O, Salvia G, Campanozzi A, et al. Use of a new thickened formula for treatment of symptomatic gastrooesophageal reflux in infants. Ital J Gastroenterol Hepatol. 1997; 29: 237-242. Bailey DJ, Andres JM, Danek GD, Pineiro-Carrero VM. Lack of efficacy of thickened feeding as treatment for gastroesophageal reflux. J Pediatr. 1987; 110: 187189. Orenstein SR, Magill HL, Brooks P. Thickening of infant feedings for therapy of gastroesophageal reflux. J Pediatr. 1987; 110: 181-186 and
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Smoking and dementia in male British doctors: prospective study A formula was incomplete in this paper by Richard Doll and colleagues 22 April, pp 1097-102 ; . In the last sentence of the statistical methods section the formula for the 95% confidence limit of the relative risk should have been given as: "exp b SE1.96 ; [not exp b SE 1.96 ; ], where b is the log relative risk and SE its standard error." Editor's choice Some errors in the BMJ lie dormant for quite some time before detection, as has happened with a reference cited in Editor's Choice from 10 April 1999 vol 318 ; . In the first paragraph the image of the "champagne glass of world poverty" was wrongly attributed to a World Bank report. In fact, it can be found in the United Nations Development Programme's Human Development Report 1992 at undp hdro 92 . Medicine and the media In the article entitled "The steady drip of biased reporting" 20 May, p 1414 ; we misquoted Claire Rayner in the last paragraph. The final sentence should have started: "If the NHS has been fatally flawed.
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The administrative cost of collection cannot easily be calculated as costs are spread across several sections and budget codes. It is recommended that a cost of collection analysis should be undertaken to assess whether most of the smaller revenue sources are worth collecting. The use of budget codes for revenue collection should be standardised across sections and or brought under a single cost centre. Arrears on all sources of revenues are considerable. At the end of 1998, the main revenue sources to the general rate fund were in over K 4.6 billion arrears see table below ; . The outstanding arrears are almost three times larger than the revenue actually collected from these sources in 1998. There are reports of undue interference from within and outside the KCC in the treatment of arrears. Table 8: Arrears on the Main Revenue Sources of the General Rate Fund, 1998.
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